The Target of Penicillin

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Frontmatter -- Preface -- CONTENTS -- CONTRIBUTORS AND PARTICIPANTS -- INTRODUCTION -- THE BACTERIAL CELL WALL - STRUCTURE AND FUNCTION / Salton, Milton R. J. -- PART I. PRIMARY AND THREE DIMENSIONAL STRUCTURE OF MUREIN -- PRIMARY STRUCTURES OF MUREIN AND PSEUDOMUREIN / Schleifer, Karl Heinz / Kandier, Otto -- STRUCTURE OF THE PEPTIDOGLYCAN OF THE CYANOBACTERIUM SYNECHOCYSTIS PCC 6714 / Jürgens, Uwe Johannes / Drews, Gerhart / Weckesser, Jürgen / Naumann, Dieter -- CHARACTERIZATION OF MUROPEPTIDES RELEASED FROM MUREIN OF CAULO-BACTER CRESCENTUS BY ENDO-N-ACETYLMURAMIDASE / Markiewicz, Zdzislaw / Glauner, Bernd / Schwarz, Uli -- THE ANALYSIS OF MUREIN COMPOSITION WITH HIGH-PRESSURE-LIQUID CHROMATOGRAPHY / Glauner, Bernd / Schwarz, Uli -- THE ANIONIC NATURE AND SOME PERMEABILITY CHARACTERISTICS OF MUREIN / Beveridge, T.J. -- ELECTROCHEMICAL AND MECHANICAL INTERACTIONS IN BACILLUS SPORE AND VEGETATIVE MUREINS / Marquis, Robert E. / Bender, Gary R. / Carstensen, Edwin L. / Child, Sally Z. -- THE STATE OF ORDER OF BACTERIAL PEPTIDOGLYCAN / Labischinski, Harald / Barnickel, Gerhard / Naumann, Dieter -- A THREE DIMENSIONAL MODEL OF THE MUREIN LAYER EXPLAINING ONE STEP OF ITS BIOSYNTHESIS BY SELF-ASSEMBLY / Formanek, Helmut -- COMPUTER AIDED MOLECULAR MODELLING OF THE THREEDIMENSIONAL STRUCTURE OF BACTERIAL PEPTIDOGLYCAN / Barnickel, Gerhard / Naumann, Dieter / Bradaczek, Hans / Labischinski, Harald / Giesbrecht, Peter -- COMPARISON BETWEEN THE SUGAR CHAIN CONFORMATION IN MUREIN AND PSEUDOMUREIN / Leps, Bernd / ßarnickel, Gerhard / Bradaczek, Hans / Labischinski, Harald -- THE CONFORMATIONAL BEHAVIOUR OF THE PEPTIDE PART OF MUREIN - AN INFRARED AND RAMAN SPECTROSCOPIC STUDY / Naumann, Dieter / Fischer, Erwin / Rönspeck, Wolfgang / Barnickel, Gerhard / Labischinski, Harald / Bradaczek, Hans -- DYNAMIC ASPECTS OF BACTERIAL CELL WALLS PROBED BY IN VIVO 15N NMR / Lapidot, Aviva / Inbar, Livia -- A NOVEL AND RAPID METHOD FOR IDENTIFYING IMPORTANT CELL WALL PARAMETERS: FOURIER-TRANSFORM INFRARED SPECTROSCOPY / Naumann, Dieter / Labischinski, Harald / Barnickel, Gerhard / Giesbrecht, Peter -- CALORIMETRIC STUDIES ON THE BINDING OF VANCOMYCIN - LIKE ANTIBIOTICS TO PEPTIDOGLYCAN / Laynez, Jose / Rodriguez-Tébar, Alfredo / Arán, Vicente / Vázquez, David -- PART II. MODELS FOR THE GROWTH OF THE MUREIN SACCULUS -- THE SHAPES OF GRAM-NEGATIVE ORGANISMS: VARI ABLE-T MODELS / Koch, Arthur L. -- MUREIN RING STRICTURE AND BIOSYNTHESIS IN GRAM-NEGATIVE BACTERIA: SOME TENTATIVE CONTEMPLATIONS / Pelzer, Helmut -- REGULATION OF THE INITIA1ICN AND OCMPLETICK OF ENVELOPE GRCWIH SITES IN STREPTOCOCCUS FAECIUM (ATCC 9790) / Higgins, Michael L. / Gibson, Carolyn W. / Daneo-Moore, Lolita -- A NEW MODEL FDR GROWTH OF THE MUREIN SACCULUS / Burman, Lars G. / Park, James T. -- PEPTIDE CROSSBRIDGES IN THE MUREIN OF ESCHERICHIA COLI ARE BROKEN AND REFORMED AS THE BACTERIUM GROWS / Goodell, E. Wm. -- A NOVEL HYPOTHESIS TO EXPLAIN REGULATION OF THE MUREIN SACCULUS SHAPE / Satta, Giuseppe / Canepari, Pietro / Fontana, Roberta -- GENERAL PROPERTIES OF TEMPERATURE-SENSITIVE CELL DIVISION MUTANTS OF STREPTOCOCCUS FAECIUM / Canepari, Pietro / Lle¿, Maria del Mar / Fontana, Roberta / Satta, Giuseppe / Daneo-Moore, Lolita / Shockman, Gerald D. -- PREMATURE DIVISION IN ESCHERICHIA COLI IN THE PRESENCE OF TRIS-EDTA / Nanninga, Nanne / den Blaauwen, Tanneke / Nederlof, Petra M. / de Boer, Piet -- PART III. FUNCTION OF MUREIN HYDROLASES AND CONTROL OF MUREIN DEGRADATION -- MUREIN HYDROLASES - ENZYMES IN SEARCH OF A PHYSIOLOGICAL FUNCTION? / Tomasz, Alexander -- THE AUTOLYTIC SYSTEM OF STREPTOCOCCUS FAECIUM / Shockman, Gerald D. / Kawamura, Takashi / Barrett, John / Dolinger, David -- INTERACTION BETWEEN CHOLINE AND THE N-ACETYL-MURAMYL-L-ALANINEAMIDASE OF STREPTOCOCCUS PNEUMONIAE / Briese, Thomas / Hakenbeck, Regine -- THE INFLUENCE OF LIPOTEICHOIC ACIDS ON THE AUTOLYTIC ACTIVITY OF STAPHYLOCOCCUS AUREUS / Fischer, Werner / Koch, Hans Uwe -- COENZYME A-GLUTATHIONE DISULFIDE: AN ENDOGENOUS INHIBITOR OF THE LYTIC ENZYMES IN ESCHERICHIA COLI / Höltje, Joachim-Volker -- AUTOLYSIS OF ESCHERICHIA COLI INDUCTION AND CONTROL / van Heijenoort, Jean / Leduc, Mireille / Heijenoort, Yveline van / Kasra, Rouha / Fréhel, Claude -- EXPRESSION OF ØX174 LYSIS GENE CLONED INTO DIFFERENT PLASMIDS / Henrich, Bernhard / Lubitz, Werner / Plapp, Roland -- LOCALISATION OF THE BACTERIOPHAGE ØX1.74 LYSIS GENE PRODUCT IN THE CELL ENVELOPE OF ESCHERICHIA COLI / Bläsi, U. / Geisen, R. / Lubitzt, W. / Henrich, B. / Plapp, R. -- INDUCTION OF CELL LYSIS BY MECILLINAM PLUS NOCARDICIN A: ISOLATION AND PROPERTIES OF A TOLERANT MUTANT / Berenguer, José / Pedro, Miguel A. de / Vázquez, David -- INCREASED WALL AUTOLYSIS AND DECREASED PEPTIDOGLYCAN CROSSLINKING IN METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS GROWN IN THE PRESENCE OF METHICILLIN / Wilkinson, Brian J. / Qoronfleh, M. Walid -- MORPHOLOGICAL STUDY OF THERMOSENSITIVE LYSIS MUTANTS OF BACILLUS SUBTILIS / Brandt, Cyrille / Karamata, Dimitri -- CHARACTERISTICS OF TOLERANT GROUP A STREPTOCOCCI / Gutmann, Laurent / Billot-Klein, Danielle / Williamson, Russell -- CELL WALL METABOLISM IN LYT-MUTANTS OF BACILLUS SUBTILIS / Meyer, P.D. / Wouters, J.T.M. -- RESTORATION OF PENICILLIN-DAMAGED CELL WALLS BY DE NOVO MUREIN SYNTHESIS AND SUCCESSIVE MUREIN DEGRADATION IN STAPHYLOCOCCI, REVEALING A HITHERTO UNKNOWN MECHANISM OF PENICILLIN ACTION: BLOCKAGE OF AUTOLYTIC WALL PROCESSES BY PENICILLIN / Giesbrecht, Peter / Morioka, Hiroyuki / Krüger, Dominique / Kersten, Thomas / Wecke, Jörg -- ß-LACTAM ANTIBIOTICS DO NOT TRIGGER THE ACTIVITIES OF AUTOLYSINS IN ETHER PERMEABILIZED ESCHERICHIA COLI / Raible, Angelika / Pelzer, Helmut -- O-ACETYLATION AND HYDROLASES OF GONOCOCCAL PEPTIDOGLYCAN / Perkins, Harold R. / Chapman, Stephen J. / Blundell, J. Keith -- ACETYLATION IN DIFFERENT PHASES OF GROWTH OF STAPHYLOCOCCI AND THEIR RELATION TO CELL WALL DEGRADABILITY BY LYSOZYME / Johannsen, Lars / Labischinski, Harald / Burghaus, Petra / Giesbrech, Peter -- EFFECT OF PENICILLIN"AND CHLORAMPHENICOL-TREATMENT ON THE MUREIN IN STREPTOCOCCUS PNEUMONIAE : ALTERATION IN STRUCTURE AND SUSCEPTIBILITY TO MUREIN HYDROLASES / Nöthling, Roswitha / Hakenbeck, Regine / Johannsen, Lars -- MICROCALORIMETRIC AND ELECTRON MICROSCOPIC INVESTIGATION ON STAPHYLOCOCCI BEFORE AND AFTER TREATMENT WITH PENICILLIN AND CHLORAMPHENICOL AND THEIR COMBINATIONS / Krüger, Dominique / Giesbrecht, Peter -- CORRELATION OF CELL WALL TURNOVER AND AUTOLYTIC ACTIVITY IN FLA AND SUPERMOTILE MUTANTS OF BACILLUS SUBTILIS / Pooley, Harold M. / Karamata, Dimitri -- B. SUBTILIS W23/168 RECOMBINANTS WITH HYBRID CELL WALLS AND PHAGE RESISTANCE PATTERNS / Monod, Michel / Pooley, Harold / Karamata, Dimitri -- PART IV. BIOLOGICAL PROPERTIES AND MEDICAL ASPECTS OF MUREIN -- IMMUNOMODULATING PROPERTIES OE NATURAL AND SYNTHETIC MUROPEPTIDES / Lederer, Edgar -- THE IMMUNOCHEMISTRY OF PEPTIDOGLYCAN / Seidl, Peter H. / Franken, Norbert / Schleifer, Karl H. -- A NEW MUREIN HYDROLASE IN HUMAN SERUM / Mollner, Stefan / Braun, Volkmar -- LYSOZYME-RESISTANT Q-ACETYLATED PEPTIDOGLYCAN OF NEISSERIA GONORRHOEAE : STRAIN VARIATION, RESISTANCE TO HUMAN PEPTIDOGLYCAN HYDROLASES, AND PATHOBIOLOGICAL PROPERTIES / Rosenthal, Raoul S. / Swim, Scott C. / Folkening, W. Joseph / Petersen, Bruce H. / Fouts, Rebecca L. / Phadke, Kalindi -- THE INFLUENCE OF DIFFERENT ANTIBIOTICS ON THE DEGREE OF O-ACETYLATION OF STAPHYLOCOCCAL CELL WALLS / Burghaus, Petra / Johannsen, Lars / Naumann, Dieter / Labischinski, Harald / Bradaczek, Hans / Giesbrecht, Peter -- CELL WALL DEGRADATION OF STAPHYLOCOCCUS AUREUS BY AUTOLYSINS AND LYSOZYME / Blümel, Peter / Reinicke, Bernhard / Lahav, Meir / Giesbrecht, Peter -- CELL WALL DEGRADATION OF ANTIBIOTIC-TREATED STAPHYLOCOCCI UNDER PHAGOCYTE-SPECIFIC CONDITIONS: Distinction between Penicillin-Induced Lytic Effects and Wall Alterations Caused by Anticoagulants / Wecke, Jörg / Lahav, Meir / Ginsburg, Isaac / Kwa, Elli / Giesbrecht, Peter -- INDUCED AUTOLYTIC WALL PROCESSES IN HEAT-INACTIVATED STAPHYLOCOCCUS AUREUS / Lahav, Meir / Ginsburg, Isaac / Kersten, Thomas / Wecke, Jörg / Giesbrecht, Peter -- CATIONIC POLYELECTROLYTES ACTIVATE AUTOLYTIC WALL ENZYMES IN STAPHYLOCOCCUS AUREUS: Modulation by anionic polyelectrolytes in relation to the survival of bacterial constituents in tissues / Ginsburg, Isaac / Lahav, Meir -- PART V. STRUCTURE AND FUNCTION OF PENICILLIN-BINDING PROTEINS -- PENICILLIN BINDING PROTEINS AS TARGETS OF THE LETHAL EFFECTS OF ß-LACTAM ANTIBIOTICS / Strominger, Jack L. -- BINDING SPECIFICITIES OF PENICILLIN BINDING PROTEINS - A CONFORMATIONAL APPROACH / Rao, V.S.R. -- THE ACTIVE SITES OF THE D-ALANYL-D-ALANINE-CLEAVING PEPTIDASES / Charlier, Paulette / Dideberg, Otto / Dive, Georges / Dusart, Jean / Frère, Jean-Marie / Ghuysen, Jean-Marie / Joris, Bernard / Lamotte-Brasseur, Josette / Leyh-Bouille, Mélina / Nguyen-Distèche, Martine -- X-RAY STRUCTURE OF A PENICILLIN TARGET ENZYME / Kelly, Judith A. -- THE FINE ARCHITECTURE AND FUNCTION OF THE GENE CODING FOR PBP-3 OF ESCHERICHIA COLI / Maruyama, J.N. / Yamamoto, A. / Maruyama, T. / Hirota, Y. -- SEQUENCE OF PENICILLIN-BINDING PROTEIN 5 OF ESCHERICHIA COLI / Broome-Smith, Jenny / Edelman, Alex / Spratt, Brian G. -- PURIFICATION AND IDENTIFICATION OF THE Pseudomonas aeruginosa DD-ENDOPEPTIDASE AS A PENICILLIN-BINDING PROTEIN / Montilla, Juan-Carlos / Rodríguez-Tébar, Alfredo / Vázquez, David -- PURIFICATION OF PENICILLIN BINDING PROTEINS FROM STREPTOCOCCUS PNEUMONIAE / Hakenbeck, Regine -- CHARACTERIZATION OF PENICILLIN BINDING PROTEINS FROM STREPTOCOCCUS PNEUMONIAE BY PROTEOLYSIS / Ellerbrok, Heinz / Hakenbeck, Regine -- DISTRIBUTION OF PENICILLIN-BINDING PROTEINS WITHIN THE CELL ENVELOPE OF Escherichia coli / Rodríguez-Tébar, Alfredo / Barbas, Julio A. / Vázquez, David -- LABELLING AND CROSS-LINKING OF E. COLI PBPs WITH BIS-B-LACTAM AND PHOTOREACTIVE DERIVATIVES OF B-LACTAM ANTIBIOTICS / Aran, V. / Rodriguez-Tebar, A. / Vazquez, D. -- TOPOLOGICAL INTERRELATION OF PENICILLIN-BINDING PROTEINS IN E. COLI - A STUDY USING CLEAVABLE CROSS-LINKERS / Said, I. Mohamed / Holtje, J. -V. -- ELECTROFOCUSING OF INTEGRAL BACTERIAL MEMBRANE PROTEINS WITH SPECIAL REGARD TO PBPs. / Botta, Giuseppe A. / Costa, Alessandro -- CHARACTERIZATION OF THE CHANGES IN PENICILLIN-BINDING PROTEINS THAT OCCUR DURING SPORULATION OF BACILLUS SUBTILIS / Buchanan, Christine E. / Sowell, Margaret O. -- PATTERN OF PENICILLIN-BINDING PROTEINS DURING THE LIFE CYCLE OF ESCHERICHIA COLI / Wientjes, F. B. / Schwarz, U. / Olijhoek, A. J. M. / Nanninga, N. -- GROWTH DEPENDENT MODIFICATIONS OF THE PENICILLIN BINDING PROTEINS OF Escherichia coli : INFORMATION SUPPORTING THE GENERALITY OF THE PROCESS AND THE MULTIPLICITY OF MECHANISMS / Rosa, E. J. de la / Pedro, M. A. de / Vazquez, D. -- RECOMBINANT PLASMIDS CARRYING PENICILLIN-BINDING PROTEIN/CELL SHAPE GENES FROM THE lip-leuS REGION OF THE ESCHERICHIA COLI CHROMOSOME / Spratt, B. G. / Broome-Smith, J. / Edelman, A. / Stoker, N. G. -- SOME ASPECTS OF THE MECHANISM OF EXPRESSION OF PBP 3 IN E.coli / Ayala, J. A. / Pedro, M. A. de / Vazquez, D. -- THE INTERDEPENDENCE OF BACTERIAL SHAPE AND SIMULTANEOUS BLOCKING OF PBP 2 AND 3 IN ESCHERICHIA COLI SP 45 AND ESCHERICHIA COLI SP 63 / Seeger, K. / Schrinner, E. -- BENZYLPENICILLIN-RESISTANT MUTANTS OF CLOSTRIDIUM PERFRINGENS / Williamson, Russell -- STUDIES OF ß-LACTAM RESISTANCE IN STREPTOCOCCUS FAECIUM / Daneo-Moore, L. / Pucci, M. / Zito, E. / Ferrero, M. -- BIOSYNTHESIS OF MUREIN (PEPTIDOGLYCAN) / Matsuhashi, M. / Nakagawa, J. / Tamaki, S. / Ishino, F. / Tomioka, S. / Park, W. -- ENZYMATIC SYNTHESIS OF PEPTIDOGLYCAN-CROSSBRIDGES IN E. COLI / Tomioka, S. / Ishino, F. / Tamaki, S. / Sudo, A. / Nakagawa, J. / Matsuhashi, M. -- NEW INSIGHTS IN THE PROCESS OF IN VITRO MUREIN SYNTHESIS IN E. COLI REVEALED BY MUREIN-ANALYSIS WITH HIGH-PRESSURE-LIQUIDCHROMATOGRAPHY / Kraus, W. / Glauner, B. / Höltje, J. -V. -- PENICILLIN-BINDING PROTEINS AND PEPTIDOGLYCAN BIOSYNTHESIS IN BACILLUS MEGATERIUM / Reynolds, Peter E. -- FUNCTION OF PENICILLIN-BINDING PROTEIN 3 IN STREPTOCOCCUS FAECIUM / Coyette, J. / Somze, A. / Briquet, J.-J. / Ghuysen, J.-M. / Fontana, R. -- THE ROLE OF A PROTEIN THAT BINDS PENICILLIN WITH SLOW KINETICS IN PHYSIO LOGY AND RESPONSE TO PENICILLIN OF STREPTOCOCCUS FAECIUM ATCC 9790 / Fontana, R. / Canepari, P. / Satta, G. -- TRANSPEPTIDATION IN STAPHYLOCOCCUS AUREUS WITH INTRINSIC RESISTANCE TO ß-LACTAM ANTIBIOTICS ("METHICILLIN RESISTANCE") / Brown, D. F. J. / Reynolds, P. E. -- PENICILLIN-SENSITIVE ENZYMES IN STAPHYLOCOCCUS AUREUS / Wyke, Anne W. / Barrie Ward, J. / Hayes, Michael V. -- VI. BIOSYNTHESIS OF MUREIN -- PEPTIDOGLYCAN BIOSYNTHESIS : CONTROL OF PRECURSOR SYNTHESIS AND INTERMEDIATES IN ASSEMBLY / Barrie Ward, J. -- CYTOPLASMIC STEPS OF PEPTIDOGLYCAN SYNTHESIS IN E. coli K 12 / Mengin-Lecreulx, D. / Flouret, B. / Parquet, C. / Heijenoort, J. van -- EFFECT OF DRUGS ON THE FORMATION AND STRUCTURE OF INTERMEDIATES OF ESCHERICHIA COLI MUREIN BIOSYNTHESIS / Mett, H. / Mirelman, D. -- THE EFFECT OF 6-LACTAM ANTIBIOTICS ON MUREIN SYNTHESIS IN ETHER TREATED ESCHERICHIA COLI / Henning, Susanne / Metz, Renate / Hammes, Walter P. -- COMPARISON OF THE EFFECTS ON MUREIN SYNTHESIS OF ß-LACTAM ANTIBIOTICS AND D-AMINO ACIDS / Criegee, Hildegard / Hammes, Walter P. -- Hildegard Criegee and Walter P. Hammes / Hara, Hiroshi / Ueda, Taro / Suzuki, Hideho -- BIOSYNTHESIS OF PEPTIDOGLYCAN IN GAFFKYA HOMARI: Processing of nascent glycan by reactivated membranes / Neuhaus, F. / Sinha, R. / Bardin, C. / Kalomiris, E. -- THE INHIBITION OF IN VITRO SYNTHESIS OF MUREIN IN GAFFKYA HOMARI BY MONOCYCLIC ß-LACTAM ANTIBIOTICS NOCARDICIN B, E AND AZTHREONAM / Wolf, Gudrun / Hammes, Walter P. -- PEPTIDOGLYCAN SYNTHESIS IN VITRO BY PARTICULATE PREPARATION FROM Streptococcus sangui s 34 / Reusch, Victor M. -- SYNTHESIS OF PEPTIDOGLYCAN FROM EXTEENALLY SUPPLIED PBECUESOES BY PARTLY AUTOLYSED CELLS OP Bacillus subtilis W23 / Harrington, Charles E. / Baddiley, James -- O-ACETYLATION OF MURAMIC ACID, BIOSYNTHESIS OF MUREIN AND THE EFFECT OF PENICILLIN G IN VIVO IN SYNCHRONIZED CELLS OF PROTEUS MIRABILIS / Gmeiner, Jobst / Sarnow, Elke -- PEPTIDOGLYCAN SYNTHESIS AND TURNOVER IN BACILLUS SUBTILIS / Wouters, J. T. M. / Meyer, P. D. -- POTENTIAL SITES FOR THE COORDINATE CONTROL OF MUREIN AND TEICHOIC ACID BIOSYNTHESIS IN S. PNEUMONIAE / Fischer, Helene / Tomasz, Alexander -- MECHANISM OF STRINGENT CONTROL OF PEPTIDOGLYCAN SYNTHESIS IN ESCHERICHIA COLI / Ishiguro, Edward E. -- INTERRELATIONSHIPS BETWEEN WALL AND MEMBRANE BIOSYNTHESIS / Rogers, H. J. / Thurman, P. F. -- FUNCTIONAL DOMAINS OF COLICIN M / Dreher, R. / Höltje, J.-V. / Braun, V. -- Author Index -- Subject Index -- Backmatter