The Archives of Internal Medicine, Vol. 16
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Excerpt from The Archives of Internal Medicine, Vol. 16: October 15, 1915
As regards the pathologic anatomy of Ravnaud's disease, Dehio's statement in 1893 obtains today, namely, that none of the published pathologic investigations, where negative findings have been reported. Are complete and detailed enough to justify the conclusion that this malady has no recognizable lesions. The positive findings include changes in the nervous system and circulatory system, either separately or in both. But such changes have been very inconstant, and their etio logic relationship to the Raynaud's disease rather indefinite, while the majority of cases autopsied have failed to reveal any lesions 'what soever. The theories as to the pathogenesis of the disease are brie¿y'
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