Respiratory Care, Vol. 38

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Excerpt from Respiratory Care, Vol. 38: November, 1993Dyspnoea is a frequent and devas tating symptom of advanced cancer. The purpose of this prospective, dou ble-blind, crossover trial was to as sess the effects of supplemental oxy gen on the intensity of dyspnoea. 14 patients with hypoxaemic dyspnoea due to advanced cancer were ran domised to receive either oxygen or air, the gases were delivered at 5 L/ min by mask. After 5 min of stable oxygen saturation (pulse oximetry), patients were crossed over to receive the other treatment. The crossover was repeated twice. Dyspnoea was assessed with a visual analogue scale (0 no dyspnoea, 100 worst dysp noea). Mean difference in dyspnoea visual analogue scale between air and oxygen treatment was (95% confidence interval to 12 patients consistently preferred oxy gen to air, similarly, the investigator consistently chose oxygen for the same 12 patients. In a global rating questionnaire, patients reported little or no benefit during the air phase compared with moderate to much benefit during the oxygen phase. We conclude that oxygen is beneficial to patients with hypoxia and dyspnoea at rest.About the PublisherForgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.comThis book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully, any imperfections that remain are intentionally left to preserve the state of such historical works.