Methods of Cancer Diagnosis, Therapy, and Prognosis

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This sixth volume in the series Methods of Cancer Diagnosis, Therapy, and Prognosis discusses Ovarian Cancer, Renal Cancer, Urogenitary Cancer, Urinary Bladder Cancer, Cervical Uterine Cancer, Skin Cancer, Leukemia, Multiple Myeloma and Sarcoma. Both standard and emerging therapies for these cancers, written by expert oncologists/pathologists in this field, are included. This fully illustrated volume Identifies biomarkers based on genetic alterations for clear cell ovarian adenocarcinoma. Identifies subgroups of ovarian cancer by using differential gene expression. Includes the application of the power-Doppler imaging for distinguishing benign from malignant complex adrenal masses in ovarian cancer. Emphasizes the advantage of using cytoreduction surgery for diagnosing advanced ovarian cancer. Provides details on the treatment of kidney cancer with radiofrequency ablation, surgery, and chemotherapy. Explains the use of immunohistochemistry for diagnosing adenomatoid tumor of the adrenal gland. Discusses the chemotherapy of testicular cancer and related second primary tumors. Includes the diagnosis of urothelial bladder cancer with urine-based tumor markers. Explains the use of immunohistochemistry and MRI for diagnosing uterine cervical cancer and describes the staging of this cancer using PET alone or PET/CT. Describes the localization of malignant melanoma using FDG-PET/CT. Explains the use of prognostic receptors for nonmelanoma skin cancer. Details the treatment of multiple myeloma using immunotherapy, radiotherapy, and targeted radionuclide therapy. Presents diagnostic immunohistochemistry of synovial and Kaposi's sarcoma. The technological advances presented in this volume are expected to expedite new discoveries and their translation to clinical practice. The field of oncology will benefit the most from these advanced methods, as a combination of therapies and personalized medicine will improve early detection of these different types of cancer. Professor Hayat has summarized the problems associated with the complexities of research publications and has been successful in editing a must-read volume for oncologists, cancer researchers, medical teachers and students of cancer biology.