Lysosomal Disorders of the Brain

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Problems with cellular lysosome function underlie a group of neurological disorders known as the storage diseases. These are inherited disorders, characterized by a failure to control the accumulation of internal cell products resulting in cell death. In recent years major advances in the fields of biochemistry and cell biology have expanded our understanding of these disorders. This book describes the molecular mechanisms and pathophysiological pathways involved and the potential for interventions aimed at treatment.