Laser-Generated Functional Nanoparticle Bioconjugates

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Annette Barchanski deals with the question how to design nanoparticles for biomedical research. She considers properties such as size, charge, biocompatibility, and functionalization of nanoparticles from a biologist’s point of view in order to achieve specific cellular responses. The author discusses the structure-function relationship of nanoparticle conjugates derived from a laser-based fabrication method. Both the limits and perspectives of tunable conjugate functions are presented, providing a general outline for researchers to configure functionalized nanoparticles with a specifically optimized design for biomedical requests, e.g. in biomedical engineering regenerative science and reproductive biology.ContentsNano-Revolution of Biomedical Science and Reproductive BiologyGold Nanoparticles: Optical and Toxicological Aspects, Membrane Interactions, Biological Application AreasDesign Criteria and Laser-Based Fabrication of Gold Nanoparticles and Gold Nanoparticle BioconjugatesYield Enhancement of Laser Ablation MethodStructure-Function Relationship: Intrinsic Parameters of Gold Nanoparticles, Conjugation ParametersLaser-Based Fabrication and Bioconjugation of  Silicon and Magnetic NanoparticlesTarget GroupsResearchers and students in the fields of nanotechnology, biomedicine, chemical engineering, laser technology, reproductive biology, and toxicologyThe AuthorAnnette Barchanski works as a scientific researcher at the Laser Zentrum Hannover e.V.