In Vitro Activities of Metal Complexes with Drugs

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This is a comprehensive guide that explores the anti-proliferative and insulin mimetic activities of heteroleptic silver, nickel, copper, and oxovanadium complexes with thiosemicarbazones and non-steroidal anti-inflammatory drugs (NSAIDs). The author, delves into the significance of metal complexes in biological and medicinal chemistry, particularly in the development of new drugs. The book outlines the synthesis and characterization of the metal complexes, followed by their in vitro activities on various cancer cell lines and insulin-resistant cell models. The results obtained from the experiments indicate that these metal complexes possess potential therapeutic properties. Moreover, the book highlights the benefits of using metal complexes with drugs over traditional drug therapy. The metal complexes exhibit improved bioavailability, better stability, and a lower toxicity profile compared to their parent drugs. Additionally, the metal complexes have shown to overcome drug resistance, making them ideal candidates for further drug development. Overall, "In Vitro Activities of Metal Complexes with Drugs" is an essential reference for researchers and students in medicinal and biological chemistry who seek to expand their knowledge on metal-based drug development. The book provides valuable insights into the synthesis and in vitro activities of metal complexes with drugs, paving the way for further research in this field.