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Handbook of Elemental Speciation

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The areas of speciation analysis have being undergoing a continual evolution and development for the last 20 years. A fundamental tool for speciation analysis has been the combination of a chromatographic separation technique with atomic spectrometry, permitting a sensitive and specific detection of the target element. Recent impressive progress toward lower detection limits in ICP-MS, toward higher resolution in separation techniques, especially capillary electrophoresis and electro-chromatography, and toward higher sensitivity in electrospray mass spectrometry for molecule-specific detection at trace levels in complex matrices has allowed new frontiers to be crossed. This first volume of The Handbook of Elemental Speciation, brings together a collection of chapters covering comprehensively different aspects of procedures for speciation analysis at the different levels starting from sample collection and storage, through sample preparation approaches to render the species chromatographable, principles of separation techniques used in speciation analysis, to the element specific detection. This already very broad coverage of analytical techniques is completed by electrochemical methods, biosensors for metal ions, radioisotope techniques and direct solid speciation techniques. Special concern is given to quality assurance and risk assessment, and speciation-relevant legislation. Each chapter is a stand-alone reference covering a given facet of elemental speciation analysis written by an expert in a given field with the volume as a whole providing an excellent introductory text and reference handbook for analytical chemists in academia, government laboratories and industry, regulatory managers, biochemists, toxicologists, clinicians, environmental scientists, and students of these disciplines. The second volume will present in detail a summary of each key element determined by speciation methods, and its detection and measurement within the four key areas of the environment, food, occupation and clinical health. .
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