Essentials of Medical Genomics

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An up-to-date edition of the groundbreaking classic Medical genomics is rapidly moving into mainstream medicine, with new and emerging technologies such as molecular genetic diagnostic tests and gene therapy having an unprecedented impact in clinical practice. Consequently, there is an urgent need for physicians and medical students to understand these developments and their evolving roles in the post-genomics era. This book fills that important need with a practical, comprehensive introduction to genomics with a focus on its impact on medical research and practice. This valuable new edition has been thoroughly and meticulously updated and expanded to include the most exciting and up-to-the-minute topics in biomedical research, including all-new chapters on multilocus SNP genotyping (SNP chips), RNAi, ChIP-chip, and genomic tiling arrays. It also includes thoroughly revised coverage of topics from the previous edition, including molecular biology, biotechnology, genome databases, bioinformatics tools, human genetic variation, genetic testing, gene therapy, microarray and related gene expression technology, analysis of microarray data, pharmacogenomics and toxico-genomics, clinical research informatics, alternative splicing, cancer genomics, proteomics, consumer genomics, and genetic data privacy and ethics. Covering concepts and techniques that are currently in use, as well as those on the cutting-edge of science, Essentials of Medical Genomics, Second Edition gives physicians and medical students everything they need to know about genomics and emerging technologies. Now 50% more comprehensive than the previous edition, and complemented with useful exercises and an appendix, this Second Edition is truly the most useful handbook available.