Enzyme Catalysis in Organic Synthesis

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Reviews for previous editions of Enzyme Catalysis in Organic Synthesis include: "an unrivalled wealth of knowledge and experience... destined to become known as "The Handbook" for biological catalysis in organic chemistry", and "this book sets the standard in the field." This completely new edition is considerably extended, and fully updated and presents the insight of numerous world-leading practitioners. The use of enzymes in organic synthesis in both academia and industry has changed from being a seldom-used technique to common practice. The power of the technology results in novel transformations, better enzymes, a wide variety of applications, and the unprecedented development of biocatalysts through the ongoing integration of molecular biology methodology in organic synthesis. This book explains how and why enzymatic catalysis has developed into the crucial synthetic tool for the chemist that it is. A major driver in research and development in the chemical industry is to employ environmentally friendly processes, often named "green" or "sustainable". Synthetic biology is also facilitated by enzyme catalysis which offers fascinating opportunities in this respect and is, and will continue to be, one of the most important tools available to scientists aiming to maintain product and process development while protecting the environment and its resources. The new edition of this renowned handbook retains the classification of biocatalytic transformations by reaction type, and this comprehensive three-volume set guides the user through the latest innovations, provides analysis of important new trends, and will be an indispensable companion for all practitioners of chemical synthesis. Herbert Waldmann, a pioneer in the field, comments in his foreword of this third edition: "It is not only an invaluable source of knowledge and references, it also embodies a treasure that consists of a multitude of findings not yet exploited by the scientific community." A must-have for all scientists working in (bio)catalysis and modern organic chemistry.