DNA Repair and Replication

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DNA Repair and Replication contains an up-to-date review of general principles of DNA replication and an overview of the multiple pathways involved in DNA repair. Specific DNA repair pathways, including base-excision repair, light-dependent direct reversal of UV-damage, nucleotide-excision repair, transcription-coupled repair, double-strand break repair, and mismatch repair, are each discussed in separate chapters. Selected Contents: -Base Excision Repair-Eukaryotic DNA Mismatch Repair-Double Strand Break Repair-Functions of DNA Polymerases-Somatic Hypermutation: A Mutational Panacea