DESIGN PROCEDURE & PREDICTIVE MODELS FOR

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Development and Application. This Ph.D. thesis concerns the development of a systematic design procedure and predictive models for solution crystallization processes, with a focus on both product and process performance. Contents include: On crystals, Crystallization, Modelling and Process Design, A Hierarchical design procedure, A predictive crystallization process model, Model implementation and numerical issues, Parameter estimation, Model validation and design of experiments, Optimal design, Appendices.