Biomarkers in Kidney Transplantation

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Biomarkers in Kidney Transplantation: Clinical Aspects and Laboratory Determinations provides a focused study on traditional and emerging biomarkers to predict early rejection of kidney transplant supporting appropriate therapeutic interventions. Coverage includes predictive and diagnostic biomarkers for different types of rejections including biomarkers of acute, chronic/sub chronic rejection or clinical rejection, both the types T-cell mediated rejection, antibody mediated rejection or mixed rejection. Comparisons are provided for broad classification of pharmacokinetic versus pharmacodynamic biomarkers, and differentiation is shown between the susceptibility, diagnostic, predictive, prognostic and monitoring biomarkers. Coverage of the analytical aspects of biomarker measurement, the process of biomarker discovery and their clinical validation addresses both the clinical features of biomarkers as well as the pitfalls of determining such biomarkers in clinical laboratories. By combining all current markers known for kidney transplant in one collection, this easy to use reference is perfect for pathologists, clinical pharmacologists and clinical laboratory scientists as well as all physicians involved in organ transplantation including immunologists and transplant surgeons.