A Study of the Microscopic Phenomena of Inflammation
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Excerpt from A Study of the Microscopic Phenomena of Inflammation: With Special Reference to the Diapedesis of the White Blood CorpuscleThe connection between the two was generally easily seen, but sometimes one occurred without the visible presence of the other, and their connection became obscured, but there came a day when the microscope was introduced into medical research and then the production of in¿ammation and fever were closely studied and light was shed on what was before darkness.By careful experiment the following facts have been proved regarding the origin of in¿ammation. First, there is, on irri tating the tissue experimented upon, a contraction, followed by a dilation of the capillaries, then a migration through the capil lary walls of leucocytes or white blood corpuscles, which spread into, and increase in the surrounding tissue then a blood stasis in the dilated capillaries and a congestion in the in¿amed area.These are accompanied by disturbance in the nutritive processes and a heightened temperature.With the thought in my mind that we learn new things only by more carefully and patiently observing old ones, I spent nearly all of the three months in the Summer of '93 in studying beneath the microscope the following phenomena of commencing in¿ammation: dilatation of the capillaries, slowing of the blood stream, and the escape of the leucocytes or white blood corpuscles from the blood vessels into the surrounding tissue.I made these observations with but little hope of discovering any new facts where such observers as Cohnheim, Lister, Stricker, Bottcher and others had so carefully and scientifically worked but simply to convince my own mind of the truth of their revelations, and to decide, if possible, certain points regarding the diapedesis cf the leucocytes which are still in dispute.It will hardly be necessary for me to state that my results con firmed their observations, and in one or two points, my observa tions, although differing somewhat from theirs, have cleared up to my own mind, disputed questions, the principal of which is that regarding the part taken by the leucocyte in its passage through the vessel wall.About the PublisherForgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.comThis book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully, any imperfections that remain are intentionally left to preserve the state of such historical works.
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